Towards Targeted MRI: New MRI Contrast Agents for Sialic Acid Detection

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Contrast agents for hepatic MRI

Liver specific contrast media (LSCM) can be subdivided according to different modalities of hepatic distribution: exclusive distribution to the hepatocellular compartment can be obtained using CM which accumulate within the hepatocytes after slow infusion; other CM demonstrate combined perfusion and hepatocyte-selective properties, with an initial distribution to the vascular-interstitial compa...

متن کامل

Two-compartment pharmacokinetic modeling of targeted molecular MRI contrast agents

Introduction Molecular MRI allows the specific detection of biomolecules that are upregulated during disease. To this extent, contrast agents (CAs) are used that home to the targeted biomolecules via high affinity ligands coupled to the CA. Activated endothelial cells in tumor angiogenesis provide well suited disease markers, which are easily accessible for circulating CAs. Several studies have...

متن کامل

Polycatechol Nanoparticle MRI Contrast Agents.

Amphiphilic triblock copolymers containing Fe(III) -catecholate complexes formulated as spherical- or cylindrical-shaped micellar nanoparticles (SMN and CMN, respectively) are described as new T1-weighted agents with high relaxivity, low cytotoxicity, and long-term stability in biological fluids. Relaxivities of both SMN and CMN exceed those of established gadolinium chelates across a wide rang...

متن کامل

Inorganic Nanoparticles for MRI Contrast Agents

O G Inorganic Nanoparticles for MRI Contrast Agents R E S By Hyon Bin Na, In Chan Song, and Taeghwan Hyeon* S R E P O R T Various inorganic nanoparticles have been used as magnetic resonance imaging (MRI) contrast agents due to their unique properties, such as large surface area and efficient contrasting effect. Since the first use of superparamagnetic iron oxide (SPIO) as a liver contrast agen...

متن کامل

MRI Contrast Agents for Pharmacological Research

The advent of the molecular imaging era has offered to pharmacologists very powerful tools for drug discovery and development, in vivo evaluation of pharmacokinetic properties, andmonitoring drug efficacy (Hargreaves, 2008; Nairne et al., 2015). In fact, molecular imaging technologies provide minimally invasive procedures to visualize, characterize, and quantify biological processes occurring a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Chemistry - A European Journal

سال: 2004

ISSN: 0947-6539,1521-3765

DOI: 10.1002/chem.200400369